N-bromobutanimide → 4-(Bromomethyl)-3-(trifluoromethyl)benzonitrile
反応式
[CH3:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].C1C(=O)N([Br:21])C(=O)C1>>[Br:21][CH2:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[C:10]([F:11])([F:12])[F:13]参加物
3
実験手順
4-Methyl-3-trifluoromethylbenzonitrile is brominated with NBS according to Example 1A to give 4-bromomethyl-3-trifluoromethylbenzonitrile. 1H NMR (400 MHz, CDCl3) δ (ppm) 7.94 (s, 1H), 7.85 (d, J=8.1 Hz, 1H), 7.76 (d, J=8.1 Hz, 1H), 4.63 (s, 2H).
出典と根拠
- ORDレコード
- ord-d893165fb6454b11800b59611e9071ea
- 出典データセット
- uspto-grants-2012_11
- 特許番号
- US08314097B2
反応ノート
読み込み中…