Acetic Acid → 2-Oxopropanal phenylhydrazone

HRID 1880327

反応式

HRID 1880327 の反応式
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(O)(=O)C.[CH:13](=O)[C:14]([CH3:16])=[O:15]>O>[C:1]1([NH:7][N:8]=[CH:13][C:14](=[O:15])[CH3:16])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

5

反応物 3

HCID 176Acetic AcidHCID 880MethylglyoxalHCID 7516Phenylhydrazine

生成物 1

HCID 2204342-Oxopropanal phenylhydrazone収率 101.3%

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

To a solution of phenylhydrazine (10.0 g, 92.5 mmol) in water (30 mL) was added acetic acid (8.8 mL) followed by the dropwise addition of pyruvaldehyde (16.7 g, 92.5 mmol) in water (400 mL) over a 15 minute period. The solution was stirred at room temperature overnight. The reaction was filtered and the resultant solid was washed with water (2×30 mL) to provide 2-oxopropanal phenylhydrazone as a yellow solid (15.2 g, 101%).

後処理

  1. filtrationThe reaction was filtered
  2. washthe resultant solid was washed with water (2×30 mL)

出典と根拠

ORDレコード
ord-99eaab2cecc9412fb4dddd46791e858b
出典データセット
uspto-grants-2012_11
特許番号
US08318762B2

関連ノート

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