Nitric Acid → HCID 67094379、化合物
反応式
[OH:1][C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]2[CH:9]=[C:8]([C:10]([OH:12])=[O:11])[S:7][C:6]=2[CH:13]=1.[N+:16]([O-])([OH:18])=[O:17]>C(OCC)(=O)C.ClCCl>[OH:1][C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]2[CH:9]=[C:8]([C:10]([OH:12])=[O:11])[S:7][C:6]=2[C:13]=1[N+:16]([O-:18])=[O:17]参加物
5
実験手順
6-Hydroxy-5-methoxy-benzo[b]thiophene-2-carboxylic acid (3.2 g) was dissolved in ethyl acetate (200 ml) and a solution of nitric acid in dichloromethane (2M, 7.7 ml) was gradually added at 0° C. into. The solution was stirred 30 min at room temperature and then it was poured into ice-cold water and filtered. The solid was washed with ethyl acetate and dried under vacuum.
後処理
- additionit was poured into ice-cold water
- filtrationfiltered
- washThe solid was washed with ethyl acetate
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-41ef2712c1854e6ea83185f5703d59ea
- 出典データセット
- uspto-grants-2012_11
- 特許番号
- US08318785B2
反応ノート
読み込み中…