Toluene → Limonene diepoxide

HRID 1881808

反応式

HRID 1881808 の反応式
CC1CC[C@@H](C(C)=C)CC=1.C([O-])([O-])=[O:12].C([O-])([O-])=O.OO.OO.OO.[Na+].[Na+].[Na+].[Na+].[C:29]1(=O)[O:34][C:32](=O)[C:31]2=CC=CC=C12.[C:40]1([CH3:46])[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1>>[CH3:46][C:40]12[O:12][CH:45]1[CH2:44][CH:43]([C:32]1([CH3:31])[O:34][CH2:29]1)[CH2:42][CH2:41]2

参加物

5

反応物 4

HCID 1140TolueneHCID 6811Phthalic AnhydrideHCID 159762Sodium percarbonateHCID 440917(+)-Limonene

生成物 1

HCID 232703Limonene diepoxide収率 99%

反応条件

温度
60 °C

実験手順

Limonene (1.36 g, 10 mmol) was dissolved in toluene (25 ml), and a composition containing sodium percarbonate (10.5 g, 66.7 mmol) and phthalic anhydride (14.8 g, 100 mmol) was added thereto. The mixture was stirred at 60° C. After 12 hours, the reaction solution was washed with water to thereby completely remove phthalic acid, sodium phthalate, and disodium phthalate, which were generated as by-products, and the remaining H2O2. Toluene was distilled off from the organic phase by distillation, and as a result, 1.66 g (99% yields) of limonene diepoxide with a GC purity of 100% was obtained.

後処理

  1. additionwas added
  2. washthe reaction solution was washed with water to thereby completely remove phthalic acid, sodium phthalate, and disodium phthalate, which
  3. distillationToluene was distilled off from the organic phase by distillation

出典と根拠

ORDレコード
ord-8e5798d827c14d6aa5c2a1d2210861c0
出典データセット
uspto-grants-2012_11
特許番号
US08318958B2

関連ノート

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