[-2,5,6-Trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-propan-1-one oxime → 1-[2,5,6-Trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-propylamine

HRID 1884353

反応式

[CH3:1][C:2]1[N:3]=[C:4]([C:22](=[N:25]O)[CH2:23][CH3:24])[C:5]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([C:13]3[C:18]([CH3:19])=[CH:17][C:16]([CH3:20])=[CH:15][C:14]=3[CH3:21])[C:6]=2[N:7]=1>CO.[Pd]>[CH3:1][C:2]1[N:3]=[C:4]([CH:22]([NH2:25])[CH2:23][CH3:24])[C:5]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([C:13]3[C:14]([CH3:21])=[CH:15][C:16]([CH3:20])=[CH:17][C:18]=3[CH3:19])[C:6]=2[N:7]=1

参加物

実験手順

Hydrogenation of 1-[-2,5,6-Trimethyl-7-(2,4,6-trimethyl phenyl )-7H-pyrrolo[2,3-d]-pyrim-idin-4-yl]-propan-1-one oxime with 10% Pd/C in MeOH using the general procedure described in Example 29 resulted in the title compound.

出典と根拠

ORDレコード: ord-d73a673fe37d48edb7b48ba7db7741d4
出典データセット: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06765008B1

反応式

参加物

反応物 1

生成物 1

試薬・触媒・溶媒 2

実験手順

出典と根拠

関連ノート