Acetic Acid → P-Toluic Acid

HRID 18854

反応式

HRID 18854 の反応式
[CH3:1][C:2]1[CH:3]=[CH:4]C(C)=[CH:6][CH:7]=1.C(ON1[C:17](=[O:18])[C:16]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:15]2[C:14]1=O)(=O)C.[O:24]=O.[C:26]([OH:29])(=[O:28])[CH3:27]>C([O-])(=O)C.[Co+2].C([O-])(=O)C.C([O-])(=O)C.[Mn+2].C([O-])(=O)C>[C:17]([OH:18])(=[O:24])[C:16]1[CH:15]=[CH:22][C:21]([C:26]([OH:29])=[O:28])=[CH:20][CH:19]=1.[CH3:1][C:2]1[CH:7]=[CH:6][C:27]([C:26]([OH:29])=[O:28])=[CH:4][CH:3]=1.[C:26]([C:27]1[CH:20]=[CH:19][C:16]([CH:17]=[O:18])=[CH:15][CH:14]=1)([OH:29])=[O:28]

参加物

9

反応物 4

HCID 176Acetic AcidHCID 977OxygenHCID 7809P-XyleneHCID 2655661,3-dioxo-2,3-dihydro-1H-isoindol-2-yl acetate

生成物 3

HCID 7470P-Toluic AcidHCID 7489Terephthalic AcidHCID 120884-Formylbenzoic acid

試薬・触媒・溶媒 2

HCID 6277Cobalt diacetate触媒HCID 12525Manganous Acetate触媒

実験手順

A mixture of 2 mmol of p-xylene, 0.1 mmol of N-acetoxyphthalimide, 0.01 mmol of cobalt(II) acetate, 0.01 mmol of manganese(II) acetate and 2 ml of acetic acid was stirred at 100° C. in an atmosphere of oxygen gas (1 atm=0.1 MPa) for 14 hours and thereby yielded terephthalic acid, p-toluic acid and p-carboxybenzaldehyde in yields of 79%, 8% and 5%, respectively.

出典と根拠

ORDレコード
ord-ae68f3c87b994f6b992ba57440c5f57a
出典データセット
uspto-grants-2010_06
特許番号
US07741514B2

関連ノート

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