Iodine chloride → HCID 14988432、化合物
反応式
[C:1]1(=[O:14])[C:11]2=[C:12]3[C:7](=[CH:8][CH:9]=[CH:10]2)[CH2:6][CH2:5][CH2:4][N:3]3[C:2]1=[O:13].[I:15]Cl>C(O)(=O)C>[I:15][C:9]1[CH:8]=[C:7]2[C:12]3=[C:11]([C:1](=[O:14])[C:2](=[O:13])[N:3]3[CH2:4][CH2:5][CH2:6]2)[CH:10]=1参加物
4
実験手順
A mixture of 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione (5 g) and iodine monochloride (5 g) in acetic acid (30 ml) was refluxed for 5 hours. After cooling, the mixture was poured into ice water and extracted with chloroform. The extract was washed with water, saturated aqueous sodium bicarbonate solution and saturated aqueous sodium chloride solution successively and then dried over anhydrous sodium sulfate. Evaporation of chloroform afforded the title compound. The compound was recrystallized from ethanol to give 6.2 g (73.8%) as dark red needles.
後処理
- temperaturewas refluxed for 5 hours
- temperatureAfter cooling
- extractionextracted with chloroform
- washThe extract was washed with water, saturated aqueous sodium bicarbonate solution and saturated aqueous sodium chloride solution successively
- dry with materialdried over anhydrous sodium sulfate
- customEvaporation of chloroform
出典と根拠
- ORDレコード
- ord-724e957875d6447f9f8437dfde8d8cd8
- 出典データセット
- uspto-grants-1992_09
- 特許番号
- US05147874
反応ノート
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