1,3-Dibromo-5,5-dimethylhydantoin → 5-(Bromomethyl)quinoxaline
反応式
[CH3:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[N:4]=[CH:5][CH:6]=[N:7]2.[Br:12]N1C(C)(C)C(=O)N(Br)C1=O.C1(C(OO)=O)C=CC=CC=1>ClC(Cl)(Cl)Cl>[Br:12][CH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[N:4]=[CH:5][CH:6]=[N:7]2参加物
5
実験手順
A mixture of 10 parts of 5-methylquinoxaline, 10 parts of 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione, 1.7 parts of benzenecarboperoxoic acid and 318 parts of tetrachloromethane was stirred for 16 hours at reflux temperature under 2 lamps of 250 Watt. The reaction mixture was cooled and the organic layer was decanted. The product was filtered off and dried, yielding 15.5 parts (100%) of 5-(bromomethyl)quinoxaline (interm. 1).
後処理
- temperatureat reflux temperature under 2 lamps of 250 Watt
- temperatureThe reaction mixture was cooled
- customthe organic layer was decanted
- filtrationThe product was filtered off
- customdried
出典と根拠
- ORDレコード
- ord-1b53b8a37c254e7782ac1e30eea796a0
- 出典データセット
- uspto-grants-1992_09
- 特許番号
- US05151421
反応ノート
読み込み中…