Thionyl Chloride → HCID 57626096、化合物
反応式
[O:1]1[CH2:5][CH2:4][CH2:3][C@H:2]1[CH2:6][O:7][C:8]1[CH:9]=[C:10]2[C:15](=[CH:16][CH:17]=1)[C:14](=[O:18])O[CH2:12][CH2:11]2.S(Cl)(Cl)=O.[CH3:23][O:24][C:25]1[CH:26]=[C:27]([NH2:39])[CH:28]=[CH:29][C:30]=1[O:31][CH2:32][CH2:33][N:34]1[CH2:38][CH2:37][CH2:36][CH2:35]1>>[CH3:23][O:24][C:25]1[CH:26]=[C:27]([N:39]2[CH2:12][CH2:11][C:10]3[C:15](=[CH:16][CH:17]=[C:8]([O:7][CH2:6][C@@H:2]4[CH2:3][CH2:4][CH2:5][O:1]4)[CH:9]=3)[C:14]2=[O:18])[CH:28]=[CH:29][C:30]=1[O:31][CH2:32][CH2:33][N:34]1[CH2:38][CH2:37][CH2:36][CH2:35]1参加物
4
実験手順
6-[(S)-1-(Tetrahydrofuran-2-yl)methoxy]isochroman-1-one was firstly converted with thionyl chloride by method B into the corresponding dichloride, and then reacted with 3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenylamine by method A. The product with the molecular weight of 466.58 (C27H34N2O5) was obtained in this way; MS (ESI): 467 (M+H+).
後処理
- customThe product with the molecular weight of 466.58 (C27H34N2O5) was obtained in this way