Thionyl Chloride → HCID 67305098、化合物
反応式
[S:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[CH2:10]O.O=S(Cl)[Cl:14]>ClCCl>[Cl:14][CH2:10][C:2]1[S:1][C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1参加物
4
実験手順
To a solution of thieno[3,2-b]pyridin-2-ylmethanol (C-4) (17 mg, 0.1 mmol) in anhydrous dichloromethane (10 mL) was added SOCl2 (120 mg). After the mixture was stirred at room temperature for 2 hours, it was concentrated and used for the next step without further purification. MS (m/z): 184 (M+1)+.
後処理
- concentrationit was concentrated
- customused for the next step without further purification
出典と根拠
- ORDレコード
- ord-11a18eba2cf64383a2ca13b696238e4a
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08507487B2
反応ノート
読み込み中…