Ethyl isocyanate → HCID 60969782、化合物

HRID 1892812ノート

反応式

HRID 1892812 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[CH2:13]([N:15]=[C:16]=[O:17])[CH3:14]>O1CCCC1>[Cl:8][C:7]1[CH:6]=[CH:5][C:4]([S:9]([NH2:12])(=[O:11])=[O:10])=[CH:3][C:2]=1[NH:1][C:16]([NH:15][CH2:13][CH3:14])=[O:17]

参加物

4

反応物 2

HCID 8022Ethyl isocyanateHCID 957943-Amino-4-chlorobenzenesulphonamide

生成物 1

HCID 60969782HCID 60969782、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

To 3-amino-4-chlorobenzenesulfonamide (420 mg) in tetrahydrofuran (2 ml) solution, ethylisocyanate (180 μl) was added and the mixture was stirred under heating and reflux for 15 hours. The reaction solution was concentrated, then the residue was recrystallized from chloroform/methanol to obtain the title compound as a crude product (550 mg).

後処理

  1. temperatureunder heating
  2. temperaturereflux for 15 hours
  3. concentrationThe reaction solution was concentrated
  4. customthe residue was recrystallized from chloroform/methanol

出典と根拠

ORDレコード
ord-00ae80a5dfa4438ea8b5277e1b3f25ac
出典データセット
uspto-grants-2013_08
特許番号
US08507714B2

反応ノート

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