Water → 1-Amino-7-bromo[1]benzothieno[3,2-c]pyridine-4-carboxamide
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]2[C:8]3[C:9]([NH:17]CC4C=CC(OC)=CC=4)=[N:10][CH:11]=[C:12]([C:15]#[N:16])[C:13]=3[S:14][C:4]=2[CH:3]=1.O.[O-:28]P([O-])([O-])=O.[K+].[K+].[K+]>OS(O)(=O)=O>[NH2:17][C:9]1[C:8]2[C:5]3[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][C:4]=3[S:14][C:13]=2[C:12]([C:15]([NH2:16])=[O:28])=[CH:11][N:10]=1参加物
5
実験手順
A solution of 7-bromo-1-[(4-methoxybenzyl)amino][1]benzothieno[3,2-c]pyridine-4-carbonitrile in conc. H2SO4 (0.04 M) was stirred at room temperature for 2 h. The mixture was poured into H2O, neutralized with K3PO4, filtered, washed with H2O and dried. The crude product was swished with MeOH to give the title compound.
後処理
- filtrationfiltered
- washwashed with H2O
- customdried
出典と根拠
- ORDレコード
- ord-02a9646cb8124e57b6fa12c8db2d2fa2
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08518964B2
反応ノート
読み込み中…