Hydrochloric Acid → Methyl 5-amino-2,2-dimethyl-4-(methylamino)-2,3-dihydrobenzofuran-7-carboxylate
反応式
[CH3:1][C:2]1([CH3:20])[CH2:6][C:5]2[C:7]([NH:18][CH3:19])=[C:8]([N+:15]([O-])=O)[CH:9]=[C:10]([C:11]([O:13][CH3:14])=[O:12])[C:4]=2[O:3]1.Cl>[Fe].CO>[NH2:15][C:8]1[CH:9]=[C:10]([C:11]([O:13][CH3:14])=[O:12])[C:4]2[O:3][C:2]([CH3:20])([CH3:1])[CH2:6][C:5]=2[C:7]=1[NH:18][CH3:19]参加物
5
実験手順
The title compound was prepared following the procedure described for Step-9 of Intermediate-1 using methyl 2,2-dimethyl-4-(methylamino)-5-nitro-2,3-dihydrobenzofuran-7-carboxylate (1.3 g), iron powder (cat. amt.), conc HCl (catalytic amount) and methanol (100.0 mL) to afford 1.1 g of desired product.
後処理
- customThe title compound was prepared
出典と根拠
- ORDレコード
- ord-904a58c5e2364c64a7b3ad3dce326531
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08519149B2
反応ノート
読み込み中…