Methacrylic Acid → HCID 23371993、化合物
反応式
[N:1]1([C:7]([O:9][CH2:10]Cl)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[K].[C:13]([OH:18])(=[O:17])[C:14]([CH3:16])=[CH2:15].C1OCCOCCOCCOCCOCCOC1>CN(C=O)C>[N:1]1([C:7]([O:9][CH2:10][O:18][C:13](=[O:17])[C:14]([CH3:16])=[CH2:15])=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1参加物
6
実験手順
Chloromethyl morpholine-4-carboxylate (1 equiv.) is added to a 0.1M solution of the potassium salt of methacrylic acid (1.1 equiv.) and 18-crown-6 (2/100 equiv.) in DMF at 0° C. After 15 min at 0° C. and a suitable time at elevated temperature the reaction mixture is filtered and concentrated to dryness under reduced pressure. The residue is purified by flash chromatography giving the wanted methacryloyloxymethyl morpholine-4-carboxylate.
後処理
- filtrationa suitable time at elevated temperature the reaction mixture is filtered
- concentrationconcentrated to dryness under reduced pressure
- customThe residue is purified by flash chromatography
出典と根拠
- ORDレコード
- ord-2308766acdac48bbb0be023c0eb251c8
- 出典データセット
- uspto-grants-1996_11
- 特許番号
- US05574097
反応ノート
読み込み中…