Hydrochloric Acid → 1-(4-Aminophenoxy)propan-2-one hydrochloride
反応式
[H][H].[N+:3]([C:6]1[CH:16]=[CH:15][C:9]([O:10][CH2:11][C:12](=[O:14])[CH3:13])=[CH:8][CH:7]=1)([O-])=O.[ClH:17]>[Pd].CO>[ClH:17].[NH2:3][C:6]1[CH:16]=[CH:15][C:9]([O:10][CH2:11][C:12](=[O:14])[CH3:13])=[CH:8][CH:7]=1参加物
6
実験手順
A stream of hydrogen was passed through a mixture comprising 19.6 g of 1-(4-nitrophenoxy)propan-2-one, 300 ml of methanol, 30 ml of concentrated aqueous hydrochloric acid and 4 g of 10% w/v palladium-on-charcoal at room temperature for 5 hours. At the end of this time, the catalyst was filtered off, and the filtrate was concentrated by evaporation under reduced pressure, to give 20 g of the title compound.
後処理
- customat room temperature
- customfor 5 hours
- filtrationAt the end of this time, the catalyst was filtered off
- concentrationthe filtrate was concentrated by evaporation under reduced pressure
出典と根拠
- ORDレコード
- ord-5621d8a6338c4b3291f55defd6f9b3b6
- 出典データセット
- uspto-grants-1996_11
- 特許番号
- US05576340
反応ノート
読み込み中…