3-(3-Amino-1H-pyrazol-1-yl)propanenitrile → HCID 54298987、化合物
反応式
[F:1][C:2]([F:8])([F:7])[CH2:3][N:4]=[C:5]=[S:6].[NH2:9][C:10]1[CH:14]=[CH:13][N:12]([CH2:15][CH2:16][C:17]#[N:18])[N:11]=1>C(#N)C>[F:1][C:2]([F:8])([F:7])[CH2:3][NH:4][C:5](=[S:6])[NH:9][C:10]1[CH:14]=[CH:13][N:12]([CH2:15][CH2:16][C:17]#[N:18])[N:11]=1参加物
4
実験手順
2,2,2-Trifluoroethylisothiocyanate (3.4 g.) was added to a solution of 3-amino-1-(2-cyanoethyl)-pyrazole (2.72 g.) in acetonitrile (10 ml.) and the solution left at room temperature for 18 hours. The mixture was evaporated to dryness and the residue recrystallised from ethanol to give 3-[3-(2,2,2-trifluoroethyl)thioureido]-1-(2-cyanoethyl)pyrazole, m.p. 164°-165°.
後処理
- customThe mixture was evaporated to dryness
- customthe residue recrystallised from ethanol
出典と根拠
- ORDレコード
- ord-64eb143b8f6f40d9b506d8cf040ea338
- 出典データセット
- uspto-grants-1982_12
- 特許番号
- US04362728
反応ノート
読み込み中…