Phenol → HCID 12881148、化合物

HRID 1902584

反応式

HRID 1902584 の反応式
Cl[C:2]1[C:7]([Cl:8])=[C:6](Cl)[C:5]([Cl:10])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[C:14]1([OH:20])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[C:21](=[O:24])([O-])[O-].[K+].[K+]>[OH-].[Na+]>[Cl:8][C:7]1[C:2]([O:20][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:3]([N+:11]([O-:13])=[O:12])[CH:4]=[C:5]([Cl:10])[C:6]=1[O:24][C:21]1[CH:6]=[CH:7][CH:2]=[CH:3][CH:4]=1

参加物

5

反応物 3

HCID 996PhenolHCID 11430Potassium CarbonateHCID 134282,3,4,5-Tetrachloronitrobenzene

生成物 1

HCID 12881148HCID 12881148、化合物

試薬・触媒・溶媒 1

HCID 14798Sodium Hydroxide溶媒

反応条件

温度
160 °C

実験手順

A mixture of 52.4 gm of 2,3,4,5-tetrachloro-1-nitro-benzene, 122 gm of phenol and 60 gm of potassium carbonate was heated for 11/2 hours at 160° C. Thereafter, the still hot reaction mixture was stirred into 1.2 liters of 2 N sodium hydroxide, and the precipitated product was collected by suction filtration and recrystallized from 300 ml of ethyl acetate. 70.5 gm (93.8% of theory) of the title compound, m.p. 164° C., were obtained.

後処理

  1. filtrationthe precipitated product was collected by suction filtration
  2. customrecrystallized from 300 ml of ethyl acetate

出典と根拠

ORDレコード
ord-508ef23d214848a7954823fff63c343f
出典データセット
uspto-grants-1982_12
特許番号
US04364875

関連ノート

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