Hydrochloric Acid → 3,6-Dimethyl-1-phenyl-3-azabicyclo[3.1.0]hexane hydrochloride
反応式
[CH3:1][N:2]1[C:9](=O)[CH:6]2[CH:7]([CH3:8])[CH:5]2[C:3]1=O.COCCO[AlH2-]O[CH2:18][CH2:19]OC.[Na+].[OH-].[Na+].[ClH:25]>C1C=CC=CC=1>[ClH:25].[CH3:1][N:2]1[CH2:9][CH:6]2[C:5]([C:19]3[CH:18]=[CH:7][CH:6]=[CH:5][CH:3]=3)([CH:7]2[CH3:8])[CH2:3]1参加物
6
実験手順
To a stirred solution of N,3-dimethylcyclopropane-1,2-dicarboximide (U.S. Pat. No. 3,166,571, Ex. 2) in benzene is added Vitride® for several minutes. This solution is stirred at ambient temperature for several hours, refluxed for one hour, and then cooled and combined with sodium hydroxide and worked-up and converted to the hydrochloride to give the title product.
後処理
- temperaturerefluxed for one hour
- temperaturecooled
出典と根拠
- ORDレコード
- ord-e2f9cb06bce747958e75bd3488e652ce
- 出典データセット
- uspto-grants-1984_03
- 特許番号
- US04435419
反応ノート
読み込み中…