Dichlorphenamide → HCID 13290231、化合物

HRID 1903721

反応式

HRID 1903721 の反応式
C[O-].[Na+:3].[Na].[Cl:5][C:6]1[C:11]([Cl:12])=[CH:10][C:9]([S:13]([NH2:16])(=[O:15])=[O:14])=[CH:8][C:7]=1[S:17]([NH2:20])(=[O:19])=[O:18]>CO>[Na+:3].[Cl:5][C:6]1[C:11]([Cl:12])=[CH:10][C:9]([S:13]([NH-:16])(=[O:14])=[O:15])=[CH:8][C:7]=1[S:17]([NH2:20])(=[O:19])=[O:18]

参加物

5

反応物 3

HCID 3038DichlorphenamideHCID 5360545SodiumHCID 10942334Sodium Methoxide

生成物 1

HCID 13290231HCID 13290231、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

反応条件

温度
25 °C

実験手順

To a solution of sodium methoxide (5.0 millimoles) in methanol (100 ml), freshly generated by the careful portionwise additions of sodium (1.15 g, 5.0 millimole) to methanol (100 ml.), is added 4,5-dichloro-m-benzenedisulfonamide (15.16 g, 5.0 millimole) with stirring at 25° C. The resulting mixture is stirred at 25° C. for 30 minutes to provide a colorless solution which is filtered. Evaporation of the clear, colorless filtrate at 40° C. in vacuo provides a solid residue which is dried in vacuo at 80° C. for 16 hours to provide analytically pure 4,5-dichloro-m-benzenedisulfonamide mono sodium salt as a colorless solid (14.0 g., 85%), m.p./252°-244° C.

後処理

  1. stirringThe resulting mixture is stirred at 25° C. for 30 minutes
  2. customto provide a colorless solution which
  3. filtrationis filtered
  4. customEvaporation of the clear, colorless filtrate at 40° C. in vacuo
  5. customprovides a solid residue which
  6. customis dried in vacuo at 80° C. for 16 hours

出典と根拠

ORDレコード
ord-2925a56d4c404959a9cb6dd60a74d85b
出典データセット
uspto-grants-1984_03
特許番号
US04438123

関連ノート

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