化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → Methyl 4-dimethylaminobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 4-(Dimethylamino)benzoic acid | HCID 12092 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Methyl 4-dimethylaminobenzoate | HCID 70994 | — |
反応手順
23 g of 4-dimethylaminobenzoic acid was dissolved in 200 ml of methanol to which was added 2 ml of concentrated sulfuric acid and the mixture was refluxed with heating for 2 days. After cooling, the reaction mixture was poured into an aqueous solution of sodium bicarbonate and the crystals thus deposited were collected by filtration, washed with water and dried to obtain 24 g of 4-dimethylaminobenzoic acid methyl ester having a melting point of 101° to 102° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04439519 |
| 出典データセット | uspto-grants-1984_03 |
| ORD ID | ord-05ee31fdce14478aabec7f1a824e6376 |
| 出典メモ | uspto-grants-1984_03 |