反应详情

23 g of 4-dimethylaminobenzoic acid was dissolved in 200 ml of methanol to which was added 2 ml of concentrated sulfuric acid and the mixture was refluxed with heating for 2 days. After cooling, the reaction mixture was poured into an aqueous solution of sodium bicarbonate and the crystals thus deposited were collected by filtration, washed with water and dried to obtain 24 g of 4-dimethylaminobenzoic acid methyl ester having a melting point of 101° to 102° C.

1. temperaturethe mixture was refluxed
2. temperaturewith heating for 2 days
3. temperatureAfter cooling
4. filtrationthe crystals thus deposited were collected by filtration
5. washwashed with water
6. customdried