Hydrochloric Acid → HCID 178463602、化合物

HRID 1905845ノート

反応式

HRID 1905845 の反応式
[NH2:1][C:2]([NH2:4])=[S:3].[CH2:5]([NH:7][C:8]1N=C(NCC)N=[C:10](Cl)[N:9]=1)[CH3:6].[OH-].[Na+].Cl>O1CCOCC1.O>[CH2:5]([NH:7][C:8]1[N:9]=[CH:10][N:4]=[C:2]([SH:3])[N:1]=1)[CH3:6]

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 5216SimazineHCID 14798Sodium HydroxideHCID 2723790Thiourea

生成物 1

HCID 178463602HCID 178463602、化合物

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 312751,4-Dioxane溶媒

実験手順

A mixture of 1.5 g of thiourea and 4 g of 2,4-bis(ethylamino)-6-chloro-1,3,5-triazine in a mixture of 20 ml of dioxane and 20 ml of water is refluxed with stirring for 2 hours in 100 ml flask. After cooling, the mixture is mixed with 1.6 g of 50% sodium hydroxide and stirred for 10 minutes. The resulting mixture is neutralized with hydrochloric acid and extracted with ethyl acetate. The extract is concentrated under reduced pressure to give 4 g of 2,4-bis(ethylamino-6-mercapto-1,3,5-triazine. The product can be used for preparation of the objective compound without isolation.

後処理

  1. temperatureis refluxed
  2. temperatureAfter cooling
  3. stirringstirred for 10 minutes
  4. extractionextracted with ethyl acetate
  5. concentrationThe extract is concentrated under reduced pressure

出典と根拠

ORDレコード
ord-ece3f5e15c1949ef980cc2538cacbfc1
出典データセット
uspto-grants-1987_03
特許番号
US04648898

反応ノート

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