p-Toluenesulfonic acid → Cycloheptyl-3-mercaptopropionate
反応式
[CH:1]1([OH:8])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[SH:9][CH2:10][CH2:11][C:12](O)=[O:13].C1(C)C=CC(S(O)(=O)=O)=CC=1>>[CH:1]1([O:8][C:12](=[O:13])[CH2:11][CH2:10][SH:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
4
実験手順
Into a 100 ml reaction flask equipped with stirrer, thermometer, reflux condenser and hot plate are placed 45.6 grams of cycloheptanol; 16 grams of 3-mercaptopropionic acid and 0.5 grams of paratoluene sulfonic acid. The reaction mass is heated to reflux and refluxed for a period of 12 hours. At the end of the 12 hour period, the reaction mass is cooled and distilled on a micro distillation apparatus yielding the compound having the structure: ##STR146## as confirmed by GLC, IR, NMR and mass spectral analyses.
後処理
- customInto a 100 ml reaction flask
- customequipped with stirrer
- temperaturethermometer, reflux condenser
- temperatureThe reaction mass is heated
- temperatureto reflux
- temperaturerefluxed for a period of 12 hours
- temperatureAt the end of the 12 hour period, the reaction mass is cooled
- distillationdistilled on a micro distillation apparatus
- customyielding the compound
出典と根拠
- ORDレコード
- ord-d80d42e7686f4b538ee8fd5679bfe335
- 出典データセット
- uspto-grants-1987_03
- 特許番号
- US04652670
反応ノート
読み込み中…