Aluminum → 1-(4-Carbomethoxyphenyl)propan-2-one oxime
反応式
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[C:12]([N+:14]([O-])=[O:15])[CH3:13])=[CH:7][CH:6]=1)([O:3][CH3:4])=[O:2].[Al]>O1CCCC1>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12](=[N:14][OH:15])[CH3:13])=[CH:7][CH:6]=1)([O:3][CH3:4])=[O:2]参加物
4
実験手順
1-(4-Carbomethoxyphenyl)-2-nitroprop-1-ene (31.0 g) in tetrahydrofuran (900 ml) was stirred with aluminium amalgam, made in the usual way from aluminium (13.5 g) and mercuric chloride (6.9 g). The mixture was cooled in ice and stirring was continued until reaction was complete. The slurry was filtered through celite and the filtrate was evaporated to give a cream solid (17.0 g). τ (CDCl3) 8.27 (3H, s), 6.22 (2H, s), 6.13 (3H, s), 2.63 (2H, d, J=8 Hz), 1.95 (2H, d, J=8 Hz).
後処理
- temperatureThe mixture was cooled in ice
- customwas continued until reaction
- filtrationThe slurry was filtered through celite
- customthe filtrate was evaporated
出典と根拠
- ORDレコード
- ord-bbf96c30a5dc4668a1be38495fbf7dba
- 出典データセット
- uspto-grants-1987_03
- 特許番号
- US04654371
反応ノート
読み込み中…