Hydrogen Bromide → HCID 68577348、化合物

HRID 1907865ノート

反応式

HRID 1907865 の反応式
C(OC(=O)[NH:10][CH2:11][CH2:12][C:13]1[N:14]([CH3:26])[C:15](=[O:25])[CH:16]=[C:17]([C:19]2[CH:24]=[CH:23][N:22]=[CH:21][N:20]=2)[N:18]=1)C1C=CC=CC=1.[BrH:28]>C(O)(=O)C>[BrH:28].[NH2:10][CH2:11][CH2:12][C:13]1[N:14]([CH3:26])[C:15](=[O:25])[CH:16]=[C:17]([C:19]2[CH:24]=[CH:23][N:22]=[CH:21][N:20]=2)[N:18]=1

参加物

4

反応物 2

HCID 260Hydrogen BromideHCID 25117356HCID 25117356、化合物

生成物 1

HCID 68577348HCID 68577348、化合物収率 97.5%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

0.085 g (0.23 mmol) of [2-(1-methyl-6-oxo-1,6-dihydro-[4,4′]bipyrimidinyl-2-yl)-ethyl]-carbamic acid benzyl ester was dissolved in 0.164 g (1.16 mmol) of hydrobromide acid in acetic acid. The resulting mixture was stirred at room temperature for 2 h. The resulting precipitate was filtered, washed with diethyl ether and dried to afford 0.07 g of a yellow compound.

後処理

  1. filtrationThe resulting precipitate was filtered
  2. washwashed with diethyl ether
  3. customdried

出典と根拠

ORDレコード
ord-ce78b3f87a22474cb93638a2ce474217
出典データセット
uspto-grants-2013_12
特許番号
US08598187B2

反応ノート

読み込み中…