[CH3:1][C:2]1[C:11]([S:12][CH3:13])=[C:10]([C:14]([F:20])([F:19])[C:15]([F:18])([F:17])[F:16])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].CO.[OH-].[Na+].Cl>O>[CH3:1][C:2]1[C:11]([S:12][CH3:13])=[C:10]([C:14]([F:20])([F:19])[C:15]([F:16])([F:18])[F:17])[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]530 mg (1.69 mmol) of methyl 2-methyl-3-(methylthio)-4-(pentafluoroethyl)benzoate were introduced into 10 ml of methanol and admixed with 0.5 ml of 20% strength aqueous sodium hydroxide solution. The contents were stirred at RT until a check on the reaction by thin-layer chromatography indicated complete conversion. The mixture was freed from the solvent, and the residue was taken up in a little water. The mixture was acidified with 1M hydrochloric acid, then stirred for 5 minutes and finally filtered. The residue obtained was 470 mg of clean product.
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