Aluminium lithium hydride → HCID 58689760、化合物
反応式
[H-].[H-].[H-].[H-].[Li+].[Al+3].[CH:7]1([CH2:12][N:13]([CH2:26][CH3:27])[C:14]2[C:23]([C:24]#[N:25])=[CH:22][C:21]3[CH2:20][CH2:19][CH2:18][CH2:17][C:16]=3[N:15]=2)[CH2:11][CH2:10][CH2:9][CH2:8]1>C1COCC1>[NH2:25][CH2:24][C:23]1[C:14]([N:13]([CH2:12][CH:7]2[CH2:11][CH2:10][CH2:9][CH2:8]2)[CH2:26][CH3:27])=[N:15][C:16]2[CH2:17][CH2:18][CH2:19][CH2:20][C:21]=2[CH:22]=1参加物
4
実験手順
To a suspension of LAH (0.600 g, 16 mmol) in THF (15 mL), was added a solution of 2-(cyclopentylmethyl-ethyl-amino)-5,6,7,8-tetrahydro-quinoline-3-carbonitrile (0.300 g, 1.06 mmol) in dry THF. This reaction mixture was gently refluxed for 14 h. The unreacted LAH was then quenched with a saturated solution of sodium sulfate, and the residue was filtered off and washed with diethyl ether. The washings were collected, dried over sodium sulfate, and the solvent was evaporated to provide (3-aminomethyl-5,6,7,8-tetrahydro-quinoline-2-yl)-cyclopentylmethyl-ethylamine (0.2 g, yield: 65%).