Cyclohexanone, 3,3-dimethyl- → 3,3-Dimethylcyclohexanone oxime

HRID 1913532

反応式

HRID 1913532 の反応式
Cl.[NH2:2][OH:3].C([O-])(=O)C.[Na+].[CH3:9][C:10]1([CH3:17])[CH2:15][CH2:14][CH2:13][C:12](=O)[CH2:11]1>O.CO>[CH3:9][C:10]1([CH3:17])[CH2:15][CH2:14][CH2:13][C:12](=[N:2][OH:3])[CH2:11]1

参加物

6

反応物 3

HCID 76322Cyclohexanone, 3,3-dimethyl-HCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium Acetate

生成物 1

HCID 594582653,3-Dimethylcyclohexanone oxime

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

実験手順

Hydroxylamine hydrochloride (8.76 g) was dissolved in water (100 mL). To the solution, a solution of sodium acetate (17.8 g) and 3,3-dimethylcyclohexanone (4.55 g) in methanol (20 mL) was added at room temperature, and the mixture was heated to reflux for 1.5 hours. Organic matter was extracted with ethyl acetate and dried over anhydrous sodium sulfate, and the solvent was then distilled off under reduced pressure to obtain a crude product of 3,3-dimethylcyclohexanone oxime.

後処理

  1. temperaturethe mixture was heated
  2. temperatureto reflux for 1.5 hours
  3. extractionOrganic matter was extracted with ethyl acetate
  4. dry with materialdried over anhydrous sodium sulfate
  5. distillationthe solvent was then distilled off under reduced pressure

出典と根拠

ORDレコード
ord-b8844983d42e4f96a1cab0df3d3e73db
出典データセット
uspto-grants-2013_12
特許番号
US08609710B2

関連ノート

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