Oxalyl chloride → 5-(Benzyloxy)-2-methylbenzoyl chloride

HRID 1914248ノート

反応式

HRID 1914248 の反応式
[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([CH3:18])=[C:13]([CH:17]=1)[C:14](O)=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)C([Cl:22])=O>C(Cl)Cl>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([CH3:18])=[C:13]([CH:17]=1)[C:14]([Cl:22])=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 597600475-(Benzyloxy)-2-methylbenzoic acid2 回

生成物 1

HCID 866574365-(Benzyloxy)-2-methylbenzoyl chloride

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a mixture of 3.3 g 5-(benzyloxy)-2-methylbenzoic acid (compound F1) in 80 ml DCM are added 1.4 ml of oxaloylchloride, and the reaction is stirred at RT over night under a blanket of nitrogen. The solvent is removed under reduced pressure yielding the title compound, which was used without further purification.

後処理

  1. customThe solvent is removed under reduced pressure

出典と根拠

ORDレコード
ord-17d9113c90cb4d16abc4ae1940817b67
出典データセット
uspto-grants-2013_12
特許番号
US08609848B2

反応ノート

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