Hydrazine hydrate (1:1) → HCID 58034303、化合物
反応式
[NH2:1][C:2]1[N:7]2[N:8]=[C:9]([CH3:11])[CH:10]=[C:6]2[N:5]=[CH:4][C:3]=1[C:12]([O:14]C)=O.O.[NH2:17][NH2:18]>CCO>[NH2:1][C:2]1[N:7]2[N:8]=[C:9]([CH3:11])[CH:10]=[C:6]2[N:5]=[CH:4][C:3]=1[C:12]([NH:17][NH2:18])=[O:14]参加物
4
実験手順
A 250 mL flask containing the Methyl 7-amino-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (2.1 g, 20 mmol), EtOH (55 mL), and hydrazine hydrate (20 mL) was heated to reflux for 6 hours. The mixture was allowed to cool to room temperature. The precipitated solid was filtered and washed with water (2×10 mL) to provide Compound (10-1) as a white solid.
後処理
- temperaturewas heated
- temperatureto reflux for 6 hours
- filtrationThe precipitated solid was filtered
- washwashed with water (2×10 mL)
出典と根拠
- ORDレコード
- ord-701308f0b71d4f668a7c97a6b42563de
- 出典データセット
- uspto-grants-2013_12
- 特許番号
- US08614221B2
反応ノート
読み込み中…