Hydrazine hydrate (1:1) → 1H-pyrrole-2-carbohydrazonamide

HRID 1915611ノート

反応式

HRID 1915611 の反応式
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]#[N:7].C[O-].[Na+].O.[NH2:12][NH2:13]>C(O)C.O>[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6](=[N:12][NH2:13])[NH2:7]

参加物

6

反応物 3

HCID 24654Hydrazine hydrate (1:1)HCID 138277Pyrrole-2-carbonitrileHCID 10942334Sodium Methoxide

生成物 1

HCID 1363872481H-pyrrole-2-carbohydrazonamide

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

A solution of 10 g 1H-pyrrole-2-carbonitrile and 1 eq sodium methoxide in 20 ml ethanol and stirred for 10 min. Hydrazine hydrate (3 eq.) is then added and resulting reaction mixture is stirred at room temperature for 18 h. The Reaction mixture is then diluted with water, extracted with ethyl acetate, dried over Na2SO4 and concentrated under vacuum to yield desired compound.

後処理

  1. customresulting
  2. customreaction mixture
  3. extractionextracted with ethyl acetate
  4. dry with materialdried over Na2SO4
  5. concentrationconcentrated under vacuum

出典と根拠

ORDレコード
ord-67f49f9b5f824120a12b4e9160bbdb77
出典データセット
uspto-grants-2013_12
特許番号
US08614218B2

反応ノート

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