Ethanol → Benazepril

HRID 1915999ノート

反応式

HRID 1915999 の反応式
C(O)C.[CH3:4][CH2:5][O:6][C:7]([C@@H:9]([NH:18][C@@H:19]1[C:29](=[O:30])[N:28]([CH2:31][C:32]([OH:34])=[O:33])[C:27]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[CH2:21][CH2:20]1)[CH2:10][CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:8].Cl>O>[CH3:4][CH2:5][O:6][C:7]([C@@H:9]([NH:18][C@@H:19]1[C:29](=[O:30])[N:28]([CH2:31][C:32]([OH:34])=[O:33])[C:27]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[CH2:21][CH2:20]1)[CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:8]

参加物

4

反応物 2

HCID 702EthanolHCID 5362123Benazepril hydrochloride

生成物 1

HCID 5362124Benazepril

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Ethanol and water are mixed in a vessel until a homogeneous solution is formed. Benazepril hydrochloride is added to the solvent mixture and stirred for 5 minutes until a clear solution is obtained. Polyvinyl polypyrrolidone is subsequently added and stirred for a further 10 minutes until a clear solution is obtained.

後処理

  1. customis formed
  2. customis obtained
  3. stirringstirred for a further 10 minutes until a clear solution
  4. customis obtained

出典と根拠

ORDレコード
ord-6937c635998040108e76c2d6058e6979
出典データセット
uspto-grants-2013_12
特許番号
US08617587B2

反応ノート

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