Sodium Carbonate → (R)-2-((Z)-((R)-2-amino-7-(4-fluoro-2-(6-methoxypyridin-2-yl)phenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-ylidene) aminooxy)-4-hydroxy-N,N-dimethylbutanamide

反応式

[NH2:1][C:2]1[N:3]=[C:4]([CH3:31])[C:5]2=[C:6]([CH2:8][C@H:9]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][C:24]=3Br)[NH:10]/[C:11]/2=[N:12]\[O:13][C@H:14]([CH2:20][CH2:21][OH:22])[C:15]([N:17]([CH3:19])[CH3:18])=[O:16])[N:7]=1.[CH3:32][O:33][C:34]1[N:39]=[C:38](B2OCCN(C3C=CC=CC=3)CCO2)[CH:37]=[CH:36][CH:35]=1.C([O-])([O-])=O.[Na+].[Na+]>C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2].CC(N(C)C)=O>[NH2:1][C:2]1[N:3]=[C:4]([CH3:31])[C:5]2=[C:6]([CH2:8][C@H:9]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][C:24]=3[C:38]3[CH:37]=[CH:36][CH:35]=[C:34]([O:33][CH3:32])[N:39]=3)[NH:10]/[C:11]/2=[N:12]\[O:13][C@H:14]([CH2:20][CH2:21][OH:22])[C:15]([N:17]([CH3:19])[CH3:18])=[O:16])[N:7]=1