Isopropyl iodide → 9H-Fluorene, 9-(1-methylethyl)-

HRID 1918426ノート

反応式

HRID 1918426 の反応式
[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Li][CH2:15][CH2:16][CH2:17]C.IC(C)C.OC1O[C@@H](CO)[C@H](O)[C@H](O)[C@H]1O>>[CH:16]([CH:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)([CH3:17])[CH3:15]

参加物

5

反応物 4

HCID 6362Isopropyl iodideHCID 6853FluoreneHCID 10219674L-AltroseHCID 178418339Butyllithium

生成物 1

HCID 186969H-Fluorene, 9-(1-methylethyl)-

実験手順

Fluorene (15.0 g, 90.4 mmol), n-BuLi (48.1 ml, 120 mmol, 2.5 M in hexane), RX=2-iodopropane (14.0 ml, 139.6 mmol). 42 was isolated as a yellowish solid (18.7 g, quant.). The analytical data were identical with these to be found in the literature (M. A. Schmidt, H. G. Alt, W. Milius, J. Organomet. Chem. 1996, 525, 15).

後処理

  1. custom42 was isolated as a yellowish solid (18.7 g, quant.)

出典と根拠

ORDレコード
ord-7e148871503b46838dc84cee25182137
出典データセット
uspto-grants-2013_12
特許番号
US08618328B2

反応ノート

読み込み中…