Iodoethane → HCID 76638406、化合物

HRID 1918436ノート

反応式

HRID 1918436 の反応式
[CH3:1][C:2]1[C:14]2[CH2:13][C:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=3[CH3:15])[C:6]=2[CH:5]=[C:4]([CH3:16])[CH:3]=1.[Li][CH2:18][CH2:19]CC.ICC>>[CH3:1][C:2]1[C:14]2[CH:13]([CH2:18][CH3:19])[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=3[CH3:15])[C:6]=2[CH:5]=[C:4]([CH3:16])[CH:3]=1

参加物

4

反応物 3

HCID 6340IodoethaneHCID 59561114HCID 59561114、化合物HCID 178418339Butyllithium

生成物 1

HCID 76638406HCID 76638406、化合物

実験手順

The substitution reaction at the 9-position was performed according to the general procedure for the synthesis of 9-substituted fluorenes described above in item IV(i). 1,3,8-Trimethylfluorene (54) (1.2 g, 5.77 mmol) was used instead of fluorene, n-BuLi (3.0 ml, 2.5 M in hexane, 7.5 mmol), RX=1-iodoethane (1.35 g, 8.65 mmol). 55 was isolated to give a white solid (1.36 g, quant.).

後処理

  1. customThe substitution reaction at the 9-position
  2. custom55 was isolated
  3. customto give a white solid (1.36 g, quant.)

出典と根拠

ORDレコード
ord-6d1b70b579a54632a5bd32fa325f12ee
出典データセット
uspto-grants-2013_12
特許番号
US08618328B2

反応ノート

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