p-Aminoacetophenone → 1-(4-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid
反応式
CC1(C)[O:9][C:8](=[O:10])[C:5]2([CH2:7][CH2:6]2)[C:4](=[O:11])O1.[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([C:20](=O)C)=[CH:16][CH:15]=1>C(O)C>[O:11]=[C:4]1[CH:5]([C:8]([OH:9])=[O:10])[CH2:7][CH2:6][N:13]1[C:14]1[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=1参加物
4
実験手順
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.500 g, 2.94 mmol) and 1-(4-aminophenyl)ethanone (1.19 g, 1.19 mmol) in ethanol (3 mL). 2-oxo-1-p-tolylpyrrolidine-3-carboxylic acid 0.644 g (quantitative) was obtained as a bright yellow solid.
後処理
- customThis compound was prepared
出典と根拠
- ORDレコード
- ord-81deef5a716d4ffbac81098960dc0466
- 出典データセット
- uspto-grants-2013_12
- 特許番号
- US08618138B2
反応ノート
読み込み中…