Thionyl Chloride → 4-Methoxy-3-nitrobenzoyl chloride

反応式

[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13].S(Cl)([Cl:17])=O>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([Cl:17])=[O:8])=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13]

参加物

反応物 2

HCID 24386Thionyl Chloride

HCID 666404-Methoxy-3-nitrobenzoic acid

生成物 1

HCID 123754634-Methoxy-3-nitrobenzoyl chloride

実験手順

4-methoxy-3-nitrobenzoic acid (10.0 g, 0.051 mol), and thionyl chloride (25 g, 0.212 mol), were refluxed together for 24 h. The reaction mixture was cooled to RT and concentrated to dryness. The off-white solid was carried onto the next step.

後処理

concentrationconcentrated to dryness

出典と根拠

ORDレコード: ord-153dd7436cdd4bf28126e895d90e9318
出典データセット: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08178557B2

反応ノート

読み込み中…