Tetralin → 5,6,7,8-Tetrahydronaphthalene-2-sulfonyl chloride
反応式
[CH:1]1[C:10]2[CH2:9][CH2:8][CH2:7][CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[Cl:11][S:12](O)(=[O:14])=[O:13]>ClCCl>[CH:9]1[C:10]2[CH2:1][CH2:2][CH2:3][CH2:4][C:5]=2[CH:6]=[CH:7][C:8]=1[S:12]([Cl:11])(=[O:14])=[O:13]参加物
4
実験手順
To a solution of commercially available 5,6,7,8-tetrahydronaphthalene (1.45 g; 11.3 mmol) in dichloromethane (22.7 mL) cooled to 0° C. was added chlorosulfonic acid (0.9 mL; 13.5 mmol) fast dropwise. The reaction mixture was stirred overnight warming to room temperature gradually. The reaction mixture was used in the next reaction directly without purification.
後処理
- customThe reaction mixture was used in the next reaction directly without purification
出典と根拠
- ORDレコード
- ord-5513d97b67ef4b5d9e62a2358e6fd01a
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08178699B2
反応ノート
読み込み中…