HCID 59600214、化合物 → HCID 66841605、化合物
反応式
[CH2:1]([O:3][C:4]([C:6]1[CH2:7][CH2:8][N:9]2[C:14](=[O:15])[CH2:13][O:12][CH2:11][C:10]=12)=[O:5])[CH3:2]>C(O)(=O)C.C(Cl)Cl.[Pt](=O)=O>[CH2:1]([O:3][C:4]([CH:6]1[CH:10]2[CH2:11][O:12][CH2:13][C:14](=[O:15])[N:9]2[CH2:8][CH2:7]1)=[O:5])[CH3:2]参加物
5
実験手順
A solution of 68 (1.056 g, 5.0 mmol) in 25 ml of acetic acid is hydrogenated over 1.056 g of platinum dioxide at RT and normal pressure for 18 hours. The black suspension is diluted with 20 ml of DCM and filtered through a pad of celite. The filtrate is evaporated to give 1.09 g of a yellow oil which is purified by chromatography (Silica gel 60, 0.063-0.2 mesh, ethyl acetate/ethanol 9:1).
後処理
- filtrationfiltered through a pad of celite
- customThe filtrate is evaporated
出典と根拠
- ORDレコード
- ord-1aff547ee02e469c8e4168ad9514da42
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08183366B2
反応ノート
読み込み中…