Toluene → Ethyl 4-benzoylbenzoate
反応式
[C:1]([C:9]1[CH:17]=[CH:16][C:12]([C:13]([OH:15])=[O:14])=[CH:11][CH:10]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:18]1(C)C=CC=C[CH:19]=1.C1(C)C=CC(S(O)(=O)=O)=CC=1>C(O)C>[C:1]([C:9]1[CH:10]=[CH:11][C:12]([C:13]([O:15][CH2:18][CH3:19])=[O:14])=[CH:16][CH:17]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
5
実験手順
A mixture of 4-benzoylbenzoic acid (20 g, 88.4 mmole), toluene (5 mL), p-toluenesulfonic acid (1 g) and ethanol (20 mL) was refluxed for 12 hours, cooled, washed with 5% sodium carbonate, and neutralized by water wash. The organic layer was dried over anhydrous magnesium sulfate and concentrated to obtain 22 g ethyl 4-benzoylbenzoate in a yield 90.5%.
後処理
- temperaturewas refluxed for 12 hours
- temperaturecooled
- washwashed with 5% sodium carbonate
- washwash
- dry with materialThe organic layer was dried over anhydrous magnesium sulfate
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-6fda9ca9a9644c6e8c3ce0b85a9009fa
- 出典データセット
- uspto-grants-2002_05
- 特許番号
- US06387942B2
反応ノート
読み込み中…