3-(4-Methoxyphenyl)-2-phenylprop-2-enoic acid → 3-(4-Methoxyphenyl)-2-phenylpropionic acid

HRID 1935734

反応式

HRID 1935734 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:11]([OH:13])=[O:12])=[CH:5][CH:4]=1>[Pd].C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:11]([OH:13])=[O:12])=[CH:7][CH:8]=1

参加物

4

反応物 1

HCID 2366983-(4-Methoxyphenyl)-2-phenylprop-2-enoic acid

生成物 1

HCID 977393-(4-Methoxyphenyl)-2-phenylpropionic acid

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 176Acetic Acid溶媒

実験手順

Palladium on activated carbon (10% wt., 2.77 g) was added to a solution of 3-(4-methoxyphenyl)-2-phenylacrylic acid (27.7 g, 0.11 mol) in acetic acid (1000 ml). The mixture was hydrogenated at ambient temperature. The mixture was filtered through Celite, and the solvent was evaporated. The product was recrystallized from a small amount of ethyl acetate. Melting point 220-221° C.

後処理

  1. customwas hydrogenated at ambient temperature
  2. filtrationThe mixture was filtered through Celite
  3. customthe solvent was evaporated
  4. customThe product was recrystallized from a small amount of ethyl acetate

出典と根拠

ORDレコード
ord-1882dce487974d0793678a129d3179de
出典データセット
uspto-grants-2002_05
特許番号
US06388090B2

関連ノート

読み込み中…