Oxalyl chloride → 2-Ethyl-6-methylbenzoyl chloride
反応式
[CH2:1]([C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:4]=1[C:5](O)=[O:6])[CH3:2].C(Cl)(=O)C([Cl:16])=O>ClCCl.CN(C=O)C>[CH2:1]([C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:4]=1[C:5]([Cl:16])=[O:6])[CH3:2]参加物
5
実験手順
A solution of 2-ethyl-6-methylbenzoic acid (49 mg, 0.30 mmol) in dichloromethane (3 mL) containing DMF (1 drop) was treated with oxalyl chloride (0.14 mL, 1.6 mmol) and the mixture was stirred for 15 h. The mixture was concentrated, azeotroping with toluene to remove traces of oxalyl chloride and the residue was used directly in the next step.
後処理
- concentrationThe mixture was concentrated
- customazeotroping with toluene
- customto remove traces of oxalyl chloride
出典と根拠
- ORDレコード
- ord-8863ec9453634770aa1fdd50a41a75a2
- 出典データセット
- uspto-grants-2002_05
- 特許番号
- US06388084B1
反応ノート
読み込み中…