Iodoform → 1-Oxo-1-(4-chlorophenyl)-3-iodo-2-propene
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH:10]=O)=[O:9])=[CH:4][CH:3]=1.[CH:12](I)(I)[I:13]>O1CCCC1.[Cl-].[Cl-].[Cr+2]>[O:9]=[C:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)[CH:10]=[CH:12][I:13]参加物
5
実験手順
This compound is prepared in a manner analogous to that of Step C of Example 4, using 6.7 grams (0.04 mole) of 4-chlorophenylglyoxal (prepared by the method of Kornblum et al., JACS, (1957), 79, 6562), 29.5 grams (0.24 mole) of anhydrous chromium(II) dichloride, and 31.5 grams (0.08 mole) of iodoform in 600 mL of tetrahydrofuran, yielding 1-oxo-1-(4-chlorophenyl)-3-iodo-2-propene.
後処理
- customThis compound is prepared in a manner analogous to that of Step C of Example 4
出典と根拠
- ORDレコード
- ord-79e1b2fc6f7e43cda9f9ca35de9b9b0a
- 出典データセット
- uspto-grants-1997_12
- 特許番号
- US05696259
反応ノート
読み込み中…