Iodoform → 1-Oxo-1-(4-chlorophenyl)-3-iodo-2-propene

HRID 1939675

反応式

HRID 1939675 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH:10]=O)=[O:9])=[CH:4][CH:3]=1.[CH:12](I)(I)[I:13]>O1CCCC1.[Cl-].[Cl-].[Cr+2]>[O:9]=[C:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)[CH:10]=[CH:12][I:13]

参加物

5

反応物 2

HCID 6374IodoformHCID 269588(4-Chlorophenyl)(oxo)acetaldehyde

生成物 1

HCID 543730961-Oxo-1-(4-chlorophenyl)-3-iodo-2-propene

試薬・触媒・溶媒 2

HCID 10197677chromium(II) dichloride触媒HCID 8028Tetrahydrofuran溶媒

実験手順

This compound is prepared in a manner analogous to that of Step C of Example 4, using 6.7 grams (0.04 mole) of 4-chlorophenylglyoxal (prepared by the method of Kornblum et al., JACS, (1957), 79, 6562), 29.5 grams (0.24 mole) of anhydrous chromium(II) dichloride, and 31.5 grams (0.08 mole) of iodoform in 600 mL of tetrahydrofuran, yielding 1-oxo-1-(4-chlorophenyl)-3-iodo-2-propene.

後処理

  1. customThis compound is prepared in a manner analogous to that of Step C of Example 4

出典と根拠

ORDレコード
ord-79e1b2fc6f7e43cda9f9ca35de9b9b0a
出典データセット
uspto-grants-1997_12
特許番号
US05696259

関連ノート

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