(E)-1-(4-chlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-one → Diniconazole

HRID 1940372

反応式

HRID 1940372 の反応式
ClC1C=CC(/C=C(/N2C=NC=N2)\C(=O)C(C)(C)C)=CC=1.[Cl:21][C:22]1[CH:27]=[C:26]([Cl:28])[CH:25]=[CH:24][C:23]=1/[CH:29]=[C:30](/[N:37]1[CH:41]=[N:40][CH:39]=[N:38]1)\[C:31](=[O:36])[C:32]([CH3:35])([CH3:34])[CH3:33].Cl.N[C@@H](CC(C)C)C(C1C=CC=CC=1)(C1C=CC=CC=1)O.Cl.N[C@@H](C)C(C1C=CC=CC=1)(C1C=CC=CC=1)O.Cl.N[C@@H](C(C)C)C(C1C=CC=CC=1)(C1C=CC=CC=1)O.Cl.N[C@@H](C)C(CC1C=CC=CC=1)(CC1C=CC=CC=1)O.Cl.N[C@@H](CC1C=CC=CC=1)CO>>[Cl:21][C:22]1[CH:27]=[C:26]([Cl:28])[CH:25]=[CH:24][C:23]=1/[CH:29]=[C:30](/[N:37]1[CH:41]=[N:40][CH:39]=[N:38]1)\[CH:31]([OH:36])[C:32]([CH3:33])([CH3:34])[CH3:35]

参加物

8

反応物 7

HCID 10913254(E)-1-(4-chlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-oneHCID 11110117(E)-1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-oneHCID 13036360(S)-2-amino-1,1-diphenyl4-methylpentan-1-ol hydrochlorideHCID 18638009(S)-2-Amino-3-methyl-1,1-diphenylbutan-1-ol hydrochlorideHCID 67707195(S)-2-amino-1,1-dibenzylpropan-1-ol hydrochlorideHCID 67707196(S)-2-Amino-1,1-diphenylpropan-1-ol hydrochlorideHCID 69017766(S)-2-amino-3-phenylpropan-1-ol hydrochloride

生成物 1

HCID 6436605Diniconazole

実験手順

Reaction was carried out in the same manner as in Example 1 except that (E)-1-(4-chlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-one was replaced by (E)-1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-one, and that (S)-2-amino-1,1-diphenyl-4-methylpentan-1-ol hydrochloride was replaced by (S)-2-amino-1,1-diphenylpropan-1-ol hydrochloride, (S)-2-amino-1,1-diphenyl-3-methylbutan-1-ol hydrochloride, (S)-2-amino-1,1-dibenzylpropan-1-ol hydrochloride and (S)-2-amino-3-phenylpropan-1-ol hydrochloride, to obtain (+)-(E)-1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-ol. The results were summarized in Table 2.

後処理

  1. customReaction

出典と根拠

ORDレコード
ord-570c2e555c7c422da35b8f1689798db0
出典データセット
uspto-grants-1997_12
特許番号
US05698742

関連ノート

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