Benzyl 4-methoxycarbonylmethyloxyphenylacetate → 4-(2-Methoxy-2-oxoethoxy)-benzeneacetic acid
反応式
[CH3:1][O:2][C:3]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]([O:16]CC2C=CC=CC=2)=[O:15])=[CH:9][CH:8]=1)=[O:4]>CO.[OH-].[OH-].[Pd+2]>[CH3:1][O:2][C:3]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]([OH:16])=[O:15])=[CH:9][CH:8]=1)=[O:4]参加物
4
実験手順
7.8 g (0.025 Mol) of benzyl 4-methoxycarbonylmethyloxyphenylacetate are exhaustively hydrogenated in 150 ml of methanol in the presence of 8 g of palladium hydroxide on charcoal at ambient temperature and under a hydrogen pressure of 50 psi. After the removal of the catalyst the mother liquor is evaporated to dryness under reduced pressure.
後処理
- customAfter the removal of the catalyst the mother liquor
- customis evaporated to dryness under reduced pressure
出典と根拠
- ORDレコード
- ord-5fcc763078524a03a5cb5d94f7393cdd
- 出典データセット
- uspto-grants-1997_12
- 特許番号
- US05700801
反応ノート
読み込み中…