Cyclohexene → (2-Amino-5-hydroxyphenyl)acetonitrile

HRID 1941534ノート

反応式

HRID 1941534 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10]CC2C=CC=CC=2)=[CH:6][C:5]=1[CH2:18][C:19]#[N:20])([O-])=O.C1CCCCC=1>[Pd].C(O)C>[C:19]([CH2:18][C:5]1[CH:6]=[C:7]([OH:10])[CH:8]=[CH:9][C:4]=1[NH2:1])#[N:20]

参加物

5

反応物 2

HCID 8079CyclohexeneHCID 14025389HCID 14025389、化合物

生成物 1

HCID 19607200(2-Amino-5-hydroxyphenyl)acetonitrile

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A suspension of 5.4 g of 2-nitro 5-benzyloxyphenylacetonitrile, 5.4 ml of cyclohexene, 22 ml of ethanol and 3 g of 10% palladium on activated charcoal was refluxed for five hours. The suspension was then hot filtered and the filtrate evaporated. The residue was recrystallised from ethanol to produce dark beige crystals.

後処理

  1. temperaturewas refluxed for five hours
  2. filtrationThe suspension was then hot filtered
  3. customthe filtrate evaporated
  4. customThe residue was recrystallised from ethanol
  5. customto produce dark beige crystals

出典と根拠

ORDレコード
ord-9f85d6aa879d4d139c24221fd3f34af8
出典データセット
uspto-grants-1997_12
特許番号
US05703266

反応ノート

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