HCID 178418361、化合物 → HCID 178461433、化合物

HRID 1943913ノート

反応式

HRID 1943913 の反応式
[CH3:1][C@H:2]1[CH2:4][C@H:3]1[C:5]1[C:13]2[C:8](=[N:9][CH:10]=[C:11]([N+:14]([O-])=O)[CH:12]=2)[NH:7][N:6]=1.[H][H]>CO.[Pd]>[CH3:1][C@H:2]1[CH2:4][C@H:3]1[C:5]1[C:13]2[C:8](=[N:9][CH:10]=[C:11]([NH2:14])[CH:12]=2)[NH:7][N:6]=1

参加物

5

反応物 2

HCID 178418361HCID 178418361、化合物HCID 178461434HCID 178461434、化合物

生成物 1

HCID 178461433HCID 178461433、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

3-(cis-2-Methylcyclopropyl)-5-nitro-1H-pyrazolo[3,4-b]pyridine (0.0462 g, 0.212 mmol) and Pd/C were taken up in MeOH. Hydrogen gas was passed through for 10 minutes, and the reaction mixture was stirred under a hydrogen atmosphere for 20 minutes. The solution was filtered through celite and concentrated to provide 3-(cis-2-methylcyclopropyl)-1H-pyrazolo[3,4-b]pyridin-5-amine as an oil, which was used without further purification.

後処理

  1. customwas passed through for 10 minutes
  2. filtrationThe solution was filtered through celite and
  3. concentrationconcentrated

出典と根拠

ORDレコード
ord-98e2f883c1334237b6a9accd73e75a67
出典データセット
uspto-grants-2013_03
特許番号
US08394795B2

反応ノート

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