Water → Sodium 3-chlorobenzene-1-sulfinate
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.C(=O)([O-])O.[Na+:16].S([O-])([O-])=O.[Na+].[Na+].O>O1CCOCC1>[Na+:16].[Cl:1][C:2]1[CH:3]=[C:4]([S:8]([O-:10])=[O:9])[CH:5]=[CH:6][CH:7]=1参加物
6
反応条件
- 温度
- 75 °C
実験手順
A solution of 3-chlorobenzenesulfonyl chloride (3.0 g) in dioxane (40 mL) was treated with a mixture of sodium hydrogen carbonate (2.7 g), sodium sulfite (3.6 g) and water (20 mL), and the resulting mixture was stirred at 75° C. for 30 minutes. The mixture was cooled to room temperature and concentrated under reduced pressure. The residue was triturated with ethanol to afford the title compound as a white solid (0.20 g).
後処理
- temperatureThe mixture was cooled to room temperature
- concentrationconcentrated under reduced pressure
- customThe residue was triturated with ethanol
出典と根拠
- ORDレコード
- ord-f782cba467544f1285cd026dab12967c
- 出典データセット
- uspto-grants-2013_03
- 特許番号
- US08394836B2
反応ノート
読み込み中…