(3,4-Dichloroisothiazol-5-yl)methanol → 3,4-Dichloro-1,2-thiazole-5-carbaldehyde
反応式
[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH2:8][OH:9])[S:4][N:3]=1>[O-2].[O-2].[Mn+4].C(Cl)(Cl)Cl>[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH:8]=[O:9])[S:4][N:3]=1参加物
4
反応条件
- 温度
- 40 °C
実験手順
A mixture of (3,4-dichloroisothiazol-5-yl)methanol (1.1 g), chloroform (150 mL) and manganese dioxide (4.7 g) was stirred at 40° C. for 20 hours. The mixture was filtered through Celite and the filtrate was concentrated under reduced pressure to afford the title compound as a yellow solid (0.62 g).
後処理
- filtrationThe mixture was filtered through Celite
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-9d36426fc4e440b4995a198cfe647ddb
- 出典データセット
- uspto-grants-2013_03
- 特許番号
- US08394836B2
反応ノート
読み込み中…