Ethyl 2-(4-chloro-2-methoxyphenoxy)acetate → (4-Chloro-2-hydroxyphenoxy)acetic acid
反応式
[Cl:1][C:2]1[CH:14]=[CH:13][C:5]([O:6][CH2:7][C:8]([O:10]CC)=[O:9])=[C:4]([O:15]C)[CH:3]=1>Br>[Cl:1][C:2]1[CH:14]=[CH:13][C:5]([O:6][CH2:7][C:8]([OH:10])=[O:9])=[C:4]([OH:15])[CH:3]=1参加物
3
実験手順
A mixture of the product from step (i) (2.7 g) in 48% aqueous hydrogen bromide (30 ml) was heated under reflux for 2 h. The solvent was evaporated, the residue washed with water and dried, yield 1.7 g.
後処理
- temperaturewas heated
- temperatureunder reflux for 2 h
- customThe solvent was evaporated
- washthe residue washed with water
- customdried
出典と根拠
- ORDレコード
- ord-2f33f75fc6134b3bbe73b114e5929d8d
- 出典データセット
- uspto-grants-2013_03
- 特許番号
- US08394986B2
反応ノート
読み込み中…